@jji666 + 1
My 2 are on the extreme side of rock, not sure if both have been mentioned?
Kittie-Female extreme metal band from London Ontario. With 6 studio albums they have enough material and notoriety to make the list. Currently there could be a heavier all female band but they were the first(extreme metal band) to my knowledge.
Martha Davis(The Motels)-Sophistication with a distinctive vocal elegance.