Why are speakers rarely satisfactory?

The vast majority of audiophiles spend decades or even their entire life searching for speakers that sound right. All of us on this forum are searching for that perfect sound. You would think that out of all the different speakers out there, there would be one that meets a persons requirements. So why are most audiophiles rarely satisfied?
There are literally hundreds of speakers on the market. Surely one of those would very closely match the preferred frequency response being sought, so what is going on here?