I have a friend whose room is a virtual cube (about as tall as it is wide and long, completely open on one side. The room is very problematic. About the only realistic thing that can be done is to listen in the nearfield, where room contribution is relatively insignificant. This requires finding speakers that sound good fairly up close to the listener (find speakers that are not too brigth). Some Spendor speakers, the JM Reynard line, for example, come to mind.
