At a minimum, you're generally going to have to adjust vertical tracking force for each cartridge, and usually anti-skating as well. Most cartridge have their own individual sweet spot within the recommende tracking force range.
Not mentioned up to this point, but it's waaaay easier to mount a cartridge on a detachable headshell AND significantly lower the risk of damaging the cantilever during the process.
Not mentioned up to this point, but it's waaaay easier to mount a cartridge on a detachable headshell AND significantly lower the risk of damaging the cantilever during the process.