If you can completely bypass the preamp in your integrated, I would go with a new preamp first. The only exception would be if your current amp doesn't have enough power to drive your speakers well.
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I recently snagged a C50/MC452 on Audiogon, replacing a MAC6700 I really enjoyed, selling it to someone on Audiogon who loves his new McIntosh.
I moved my system to a room that was more than double the size and the extra power and the improvement in sound quality was immediately appreciated!
I know lots of audiophiles look down on McIntosh electronics, but to me it has a very "musical" sound, sounds great with a wide variety of speakers and most important, can be listened to for a long time, without being "tiring" to the listener.
I really enjoy my new acquisitions!