Its certainly a step up, however, for me personally, I wonder if the additional cost would be worth it. If you do this, do post your observations.
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I'm not familiar with the Ayre, but I'm driving my F52's with a PASS X250 250 @ 8ohm 500 @ 4ohm and its a great match.
At low level I get the Class A up to 40 watts and thats where I do most of my listening then on big transients the PASS has the juice. I can presurize my room with tight articulate bass with well ballanced full sound.
I never felt A bigger amp would be worth the expense..
I have been listening to my F52s for 2 days now with a buddy using the Ayre MXRs vs V5xe and all I can say is OMG!!! I never thought they would transform the sound much - more of everything, transparency, clarity, unlimited power, nuance, etc. I am blown away - just wanted to post observations since some folks asked how it made out if I went this way.