Good question. With a set of these in my system, time and again I've considered this. Either direct replacement, or factory 'treatment'.
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I just had my Au24 Interconnects upgraded to E, and my impression of the upgrade mirrors what Artmaltman states on the Power Chord upgrade.
I was very skeptical of the upgrade but for $200.00, I figured it could not hurt in comparison with spending $$ on a new interconnect to improve my system.
I was surprised at the improvement - better focus, more lively and made the original Au24 seem veiled.