Update on Audiogon Member Almarg

I have some very sad news and information to share.

Al ( @almarg ), through his wife Margaret, asked me to post the following...

{"The attached letter to you was dictated at his bedside to me earlier today. I hope I got his words down precisely as he desired."}

"Unfortunately Al has an extremely aggressive form of Mantle Cell Lymphoma coupled with a mutation of gene TP53 (known as tumor suppressor gene). He has received outstanding advanced treatment with the latest and greatest chemo drugs at Smilow Cancer Hospital at Yale in New Haven. Unfortunately it appears that he only has a few weeks to live.

Please feel free to post a substantive update [on Audiogon]. He has not been able to do that because of his condition. Please indicate that he has enjoyed solving problems, researching others,’ and learning a good deal himself while developing his answers.

He and I wish everyone all the best of health and success in audio endeavors, in that order.

Al [and Margaret]

September 9, 2020"

I will post my very personal response tomorrow.
@ david_ten - This is very sad news. My best wishes to Al and Margaret. It is a delicate matter to identify breakthrough treatment options for late stage patients, but there are potentially significant improvements for mantle cell lymphoma in clinical development. The following study is recruiting patients: https://clinicaltrials.gov/ct2/show/NCT03088878?term=Oncternal&cntry=US&draw=2&rank=3
I am quite familiar with the program - the science is excellent, discovery program comes from UC San Diego, and my understanding is that clinical benefit is, to the extent that data have been released, quite meaningful. You may want to share this with Margret and Al.
All the best!