I find that the amp makes MUCH more of a difference in sound than any other electronic component. In the case of tube amps, there is such a wide range of sound from different topology, tube types, models, etc., that the sound can be extremely wide ranging, with many sounding less appealing, to me, than solid state amps. Among tube amps, I've heard great sound from all types of amps--single ended triode, pushpull tetrode/pentode, and output transformerless (OTL) amps so I do not think any one particular type is the best--the specific implementation and voicing matters. The OTL I particularly liked is a unique custom built amp, my favorite pushpull amp is a Western Electric 59B, and my favorite single-ended triode is probably the Audio Note Gaku-On. I suspect that the ZOTL amp can be good too, although I did not like the specific voicing of the two brands I heard (I liked the Berning, but, it is not among my favorites).
The favorite among the amps I own is a pushpull amp running Western Electric 349 output tubes. I am also a big fan of pushpull amps running 6L6 or 350B tubes. I also own, and like, the parallel 2a3 amp from Audio Note (Kageki).