Yeah, I agree that Waits really is one of a kind. My first experience with his work was hearing "Heart Attack and Vine" in college. It blew me away, and I've been a big fan ever since. "Swordfishtrombones" is my personal favorite, although there are lots of great ones to choose among. The lyrics really are just about perfect, but I also do love those "kaleidoscopic" soundscapes you mentioned. Have you heard the two Latin Playboys albums? The band is a kind of side project for members of Los Lobos, and they get that same kind of vibe, at least in terms of the sound. Much different from anything Los Lobos has done, even their more experimental records, like Colossal Head and Kiko.
Thanks for your suggestions! I will track them down.