Speakers A and B simultaneosly in different rooms

I would like to find the best way to run music simultaneously out of two sets of speakers on diffent sides of the house. What is the most effective method. Would it be to connect the amps/preamps of the the two sets (if so, how?), to use a common source with 2 outputs and run an individual line out to each amp, or to find an amp with A and B speakers, and run a long speaker wire to the next room.
Note the two sets wont be more than 20 feet apart.
Thank for the help.