I think using more than two brands of cables at any one time is enough to drive anyone crazy, and the same is true of two cables which are very different also. However, if you stumble across two cables which are generally similar in type of sound, but different in specific ways, it may work very well. After experimenting I have found that in my system using Purist Dominus interconnects and NBS Monitor 0 speaker and digital cables gives me a more detailed upper treble and especially lower bass than I could get with Dominus alone, but a warmer midrange in general, and especially lower midrange, than I could ever get with an entire system of Monitor 0, which I had for a while. But I doubt this kind of matching would ever have worked if the basic sound of the two cables wasn't generally quite close.
Single brand vs. multiple brand ICs and ACs
Occasionally someone mentions in a post that they use the same brand cable for all their components. At least once I've seen someone say that this is something to be avoided. I'm currently upgrading my system so this is a good time for me to either add or eliminate variety in my cables. Anyone interested in sharing their thoughts on this? Thanks.