Should we upgrade high end fuses?

Nicolaus Copernicus (1473-1543) was the first known modern person to propose the Earth circles the Sun. He based his theory on earlier writings and a belief that it was a more probable and elegant solution. He had no observational evidence of this theory, was challenging the religious beliefs of the time, and was accused by his peers of "wanting to over-turn the whole science of astronomy"!

Johannes Kepler (1571-1630) followed up by correctly describing the motions of the planets using geometry and science. His equations of motion are a celebrated major achievement. Even so, it took at least 100 years for most educated people to accept and believe the earth was round, and the sun was not the center of the universe.

Now audiophiles are proposing wires and fuses make a difference... Any Kepler's out there ready to step up to this?

Dave, I have experienced the differences wire can make, but have never tried high end fuses. I am open to whether they make a difference or not. Maybe I didn't make my comparative point clear.

Copernicus risked ridicule with his proposals, and eventually Kepler proved him right. Some audiophiles are being ridiculed for proposing they hear a difference with high end fuses, and I'm challenging someone to come up with the scientific proof one way or the other.

I can live with the answer either way.