Room Correction: Should I disconnect my REL Subwoofers before running room correction?


I have a NAD C 658 Streamer / Dac with Dirac room correction.  I have a pair of REL Subwoofers R 528 connected/ integrated to the mains.  I’m wondering if it would be best to run room correction with the subs connected or to run without and then tune the RELS after.  
Equipment:
Modwright150SE
Dali Euphonia ms-4
NAD C 658
REL R528 x2 
puffbojie
Room correction primarily addresses lower frequencies so they have to be on. That's the whole purpose.
Maybe the best solution is to just run RCAs to the c658 which is unfortunate because I think the high level is preferable.