A Monoprice IC will be just as good as the "high price spread". As the French chef says " No diffawrance!".
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OP I can tell you from experience that interconnects do make a difference but the trick is finding one that will synergize with your system. Take a look at Silnote interconnects. They range from 300 to 3000. I had the Morpheus line and it was very good and balanced.
if your system leans a little dark/warm take a look at Audio Envy. For best bang for your buck try Zavfino