I use a Calypso biamping with 2 Moscode 401 HRs to very good effect. Speakers Mark-Daniel Maximus Monitors.
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I have tried an Ayre V5xe, McCormack DNA225 platinum mods, and now a Simaudio W-7 with my Calypso.
I like the Simaudio the best by quite a margin.
The modded McCormack is pretty good but doesn't have the combination of warmth, detail and authority of the Sim.
It sounded now in comparison a bit less at ease/musical. The low impedence of the DNA (10K ohm) might not have been a good match for the 600 ohm balanced output of the Calypso?
Or the Sim is a better amp.
the Ayre has a good impedence match (100,000 ohm) but I thought it didn't have it the at the low end. I'm running some more challenging speakers, the Totem Mani 2 signatures.
For my mixed system, I run the Calypso with a Theta Dreadnaught I. To me, and without a practical way to compare to other systems, it sounds great. I get sharp clean highs, great mids and mostly great (and deep) bass(mostly, because my room has issues). Warm? Slightly, especially after it plays for a little while. Clear? Amazingly so. I have no complaints about this combination and feel I'm done looking for replacements.
Hope this helps.