I dunno, I think I would first identify speakers that sounded the best in my room. Then I would probably begin my search for an amp/premp combo that worked correctly with my speakers and the room in which they are placed.
After all, *everyone* here knows that the room/speaker interface is, BY FAR, the most critical metric used to obtain the best sound quality from any sound system. This is closely followed by using the very best source material available for the music I like to listen to.
After you get those parts of the system identified, you can then begin the search for the cables and such needed to eke out the last little bit of sound quality that you seek....