"Small Form Factor" OK For Media Server?

As shopping for a new PC for hard drive based music and movies continues to bore and frustrate me, I am thinking about finally striking out and attempting to build one on my own.

True to my audiophile roots, I am concerned not only about the performance, but also the quality and appearance of the chassis.

I found this case, which wouldn't stick out too badly next to my audio gear, but I would appreciate any advice from more sophisticated PC users:

http://www.xoxide.com/lian-li-pc-v300b-black.html

Would the smaller size of this case make it difficult to incorporate the latest components I might want for a media server?

Thanks for any ideas on cases or any other aspect of DIY media servers and their design and components