For me it made the biggest difference on the P300 with which I used the PS Audio xStream Statement. I used an older Synergistic research pc on the HC/UO.
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The pwr cords seem to make an improvement where ever you place them if you use hi quality after market versus stock. Having said that, I use my best cords last in the chain connected to source components.I have many Ultimate Outlets UPC-200s,P500,and other conditioning products and last seems to work best for me