here is a review of them :
I don't think of the 5350SE or the Destiny as sounding lean at all, if anything they lean the other way. Nice full round sound. The Destiny is better. I put the 5350 and it side by side and no doubt the Destiny sounds better. But the 5350 is a great amp and you get the magic that any other cheaper integrated just doesn't quite get to. I can't say I've tried them all but my experience has shown that you can't get by with a cheap amp, you will get that boxy light sound no matter what the rest of the gear is. I think you are thinking like a smart man considering the Dynaudio Focus and Creek. I have the Dynaudio Audience 42 and I mean I almost prefer it to the Revel M20 in many ways. I really want to try a higher line Dyaudio with my Destiny. I think there is a good synergy between the two. The only hang up is Dyns probably want a little more power than the Creek amps offer but if you are in a smaller type room it shouldn't be to much of a problem. I like to crank it up fairly loud so if you don't do that either it might no be an issue.