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You ask this question because you are not using properties to evaluate your music reproduction system. This has been proven in shootouts using properties to the many listeners who have heard Tru-Fi. You need to think of your music reproduction system as a complete set of individual properties that are the each optimized to work together in the music reproduction system. This has been proven many times and all listeners have found this to be true.
Those who do not use Tru-Fi in their music reproduction systems will never be happy with their sound because of the distortion. Based on your question it is clear that you love distortion and are trying to find a way to get what you think is the "best" distortion to use in your music reproduction system. But you will never be happy without using Tru-Fi you are like a little child a seeking a new toy.
The E-350 is a very well built integrated, you gain a lot of feature like pre-out/main-in, bypassable tone control and headphone output, it also has slots for D/A and phono card. If you can find one with good price and condition, I will say go for it, try it in your system, if you don't like it, you should have no problem to resell it. BTW, my experience with Accuphase is their pure class A amp is more sweet sounding.
If you want something more sweet and warm, tube amp is the answer.
I don't know what other brands you have access to. There are several other solid-state integrated's that are a little more "forgiving" than the Hegel, Luxman, Ayre, even Simaudio (in my experience). PMC's Fact series is also less forgiving than their Twenty and now Twenty5 lines. Otherwise, as already mentioned, start looking at tubes.
Although I haven't heard it I'm sure the Accuphase would be great and unless your room is huge and open 100 quality watts should be fine.
Two other amps to consider would the Marantz PM11S3 and the Yamaha A-S2100. They, along with the Accuphase have a reputation of being a bit warmer and smoother with a big full sound. Musical Fidelity also has a fuller warmer signature. Good luck.