I'm not completely certain on this, but I don't think the Adcom design is a balanced one. It may have balanced connectors, but the internal circuitry I believe is running single ended. If that is correct, I don't think you will have an appreciable difference on the connection from the CD player (or DAC in this case) to the 750, unless perhaps the DAC is a truly balanced design. Some companies, such as BAT use balanced circuit design throughout the product--for these products you should always use balanced cables when possible. However, in your case, from the pre-amp to the amp is a little different issue, particularly if you are using long interconnects or you are in a noisy (RF and EMI) area. If either of these is the case then I would recommend balanced. If it is not the case, then it's going to be tough to know for sure without trying.