If the impedance issues are within reason then I would guess it will sound good. Mac amps and Klipsch speakers have a certain synergy that is well known. I own some older Mac and Klipsch gear and can attest to the combination. Ayre sounds pretty clean and nuetral to my ears so I can't see why it would be a problem.
Mcintosh with Ayre pre-amp
I have always wanted a Mcintosh power amp and love the way they sound, but I don't know if it would pair well with my Ayre K-5xe preamp. I haven't been able to find anyone with this combination. Maybe this is an indicator that mixing Ayre with Mcintosh is a bad idea? Before I drop a few G's on a Mac amp, what would you guys advise? Thanks.