Martin Logan CLS setup

I recently obtained a pair od Martin Logan CLS IIs and just wonder if you guys could get me some pointers on setting them up for optimum performance. My room is about 22' X 26' with a very high cathedral ceiling about 20 feet at the peak. The front wall where the speakers will be has a fireplace in between the speakers with a window on each side of it. Behind the listening chair is open into the kitchen and rest on the house. Any advice on distance from back and side wall etc room treatment??

Carey