Looking for a good full range floor stander

My room is about your size, and I my listening tastes are similar. I have a pair of Zu Definitions that are definitely full range. Zu offers a 60 day home trial. 

As I noted, my space is similar to that of the OP: 45x24x16 - and it is very live with no carpets or other soft surfaces, but it does have various partitions that break up the waves - such as a free standing fireplace. If one of the OP's goals is to fill the space with music, the only option is trial and error. I auditioned several speakers that I really liked in a dealer's store or at a show, but that died in my home. It found that it easier to fill one end of the space with good sound than to fill the entire volume. I also did not want a huge monolith that would visually dominate the space. In general, I found that more sensitive speakers seemed to be a better fit. 

" We have found even if you are somewhat close to a speaker in a large room it helps but doesnt take away the feeling that the sound is not filling the room."

Agreed. And cranking up the volume does not alleviate the issue entirely. 

I am fortunate to live in an urban area - Washington, DC - with several B&M stores and distributors who are willing to cooperate with in-home auditions. Nothing is as good as an in-home experience, especially when the room is challenging. I know that the OP does not have this luxury. But it is true nonetheless.