Leaving iTunes in 24/96?

It's what the computer audio experts all say.

Drubin,
I didn't know you had to restart iTunes. How'd you find this out? Just wanted to make sure this was the case.

I'm extremely happy with iTunes and after experimenting, I cannot hear a difference thru my Yamaha HS80 studio monitors. Now, my converter is a lower end Presonus, but to be honest I think it does a decent job.

Experiment and see if the upconversion sounds okay to you.

If you are using a Mac, remember that every time you change the sample rate in Audio Midi, you need to restart iTunes for it to take effect, otherwise it will just up- or down-convert. Don't know whether or not this is also true in Windows. This step is not required if you are using Amarra or Pure Music (both are Mac only).

You can spend $300 on Amarra...it switches automatically. There is also a remote app for iPad that allows it to be used as a track pad remote and has a program for Amarra...pretty cool!

Use Media Monkey instead of ITunes. You won't have to worry about converting.
Much more superior soft to iTunes IMHO.