Is there a real difference in sound between Media Servers (without built-in DAC)?

I'm trying to choose a media server and am currently leaning toward a Bluesound Vault 2.  I would most likely connect to an MQA-compatible DAC like a Mytek.  We all know transports make a difference to sound quality, but is there a discernible difference between media servers?  The Bluesound is pretty cheap at $1,200.  Would a NAD 50.2 or Aurender or other more spendy server sound significantly better?  

Rest of the system is Line Magnetic LM 518IA 22W integrated into Merlin TSM monitors, analog is Rega RP-6/Dynavector20X2L/Heed Quasar
I'd recommend the Bluesound in a heartbeat.
The DAC in the Node 2 has gotten very good reviews, but if you want to go with a separate DAC, then a Schiit Gungy or Yggy would be my choice. Though if you absolutely need MQA then the Mytek would be a good choice.
YES. I just went from a Bryston BDP2 to the Antipodes DS GT. There is a significant difference between the two. To my ears the DS GT produces a more articulate and deep bass. Vocals are pushed forward,  creating the illusion of a deeper soundstage. There is more air and space around and between instruments/ singers. All of this is done without glare or brightness. 
Tidal was unlistenable through the BDP2. I submit I have CD quality through the DS GT. Don't take my words, try to find one to listen to and come to your own conclusions. 

MQA may not be around for long.  That is why Schiit makes its Yggy upgradeable in the event it does.
Why would two units putting out the same bit stream sound different than one another?  Isn't it the DAC(s) decoding the bit stream that would sound different?  Or are some of these servers doing some internal processing to the bit stream?  Is there the opportunity for loss of some packets with some protocols?