The short answer is yes. Have been streaming from a Roon Nucleus to a Chord Qutest for almost a year now. It replaced a Bluesound Node 2i in my main rig. From an SQ perspective I'd say that the two pieces were pretty close, but that was before I replaced the stock power supply with a 19v Sbooster Linear Power Supply. With the better LPS in place, SQ of the Nucleus as Server/Streamer surpassed that of the Node 2i. Can also note that the Nucleus is cable sensitve, and good USB and ethernet cables here do make a difference. I'm using a Curious USB Cable and Wireworld Starlight Cat 8 ethernet cable. Hope this helps.
