What speakers are you using, and what is their efficiency rating? That would make a difference.
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I have had both the 402 and 501's with a C46
I would not go to the 501's unless you are having difficulty driving the speakers you have.
You would notice a slight difference, but imo, it would just be a "flavor" difference rather than feeling one amp is better than the other(s).
Actually my preference was for the 402, as i thought it sounded a tad "sweeter/smoother" than the 501's ....