Most I2S is not over HDMI (except as Kr4 pointed out, for PS Audio), but there are several different I2S interfaces. The difference between the I2S and the common s/pdif is that the I2S includes the word clock communication, allowing a DAC to sync with a transport, minimizing jitter.
Coax (s/pdif) is superior to toslink (optical) in almost all applications (due to lower jitter amongst other things). AT&T is superior to s/pdif in most applications...
USB... can be a good interface, but many times, not very well executed. HDMI, potentially a very good interface, but contains all kinds of copy right protection which can screw up the sound...
Coax (s/pdif) is superior to toslink (optical) in almost all applications (due to lower jitter amongst other things). AT&T is superior to s/pdif in most applications...
USB... can be a good interface, but many times, not very well executed. HDMI, potentially a very good interface, but contains all kinds of copy right protection which can screw up the sound...