I blew my speaker....Please help

I connected the chiro C-300 poweramp to my Audible illusions preamp, the usual setup then I connected my speakers. I plug the chiro amp into my audioprism line conditioner and immediately the green light turned on in the amp which is in standby mode. waited for an hour to warm up , I pressed the power botton and I heard a loud pop from my speaker and noticed smoke coming out from the amp. I immmediately unplug the amp. My right speaker has been damaged, one of the drivers has no sound coming out after I hooked it up with my other amplifier. Please tell me what's wrong with my system or amp? Thanks,
Many things could be wrong with the amplifier and/or the hook-up in general. Start with taking the amp to a qualified tech, fixing that problem and then carefully reviewing speaker cable integrity. Good luck.
If possible, I suggest you contact the store you purchased the equipment from and ask them to repair or ask where you can take it for repair. If not possible, I suggest you call the Manufacturer and request a repair shop name or if you can ship the unit back to them for repair. I had the exact same problem with my Theta DAC and the local store shipped it back to the MFG for repair (4 blow power transformers). Mfg paid shippping charges both ways. Down time was 3 weeks. cheers.....
It is equally possible that your tube preamplifier could be at fault. When using a tube preamp and a solid-state amplifier the correct turn-on sequence is as follows: (a)turn on the tube preamplifier and let it stabilize for at least a minute or two before (b) turning on the amplifier. If you failed to do this, then your amplifier remained in standby mode because it sensed too much DC voltage coming from the preamp. Aside from this, the preamp may not be operating properly in that it may have an unacceptably high level of DC output which would immediately trigger the protective circuitry in the amplifier. When you attempted to bypass these circuits by pressing the on/off switch a second time, the DC may have gone into the amplifier; and if the amplifier is direct-coupled, from there into the speaker.
Depending on the age of the unit, a good store will repair it for you or pick up the cost and ship it back for you.