You should ask "Kitch" about this. He is also a wood worker and may have some tips on protecting the gear from dust (which would probably destroy the CD player and can't be good for the speakers and amp as well).
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You are going to need plenty of juice to get a moderate S in room of that size, esp. over machinery. I would think that the Bryston 4 series would be the minimum, along with a reasonably efficient pair of speakers. Any yes, the electronics and esp. CD, should be in a closed cabinet or otherwise protected from dust.
Everyone has their own idea about audio but here is my suggestion: Buy a pair of horn loaded bar type speakers and attach them to the wall with brackets. No need to get carried away with this if you want to get work done. I happen to have a pair of Klipsch Heresey ported industrials that I will be listing tomorrow. I acquired them from a bar some time ago and can attest to their performance in such a large space. Very efficient speakers that need little in the way of amplification. Very inexpensive on the used market. Good luck, Patrick