The idea of 4 subs is the correct one. In case its not clear, the problem is standing waves and this is not easily corrected by room treatment if it can be treated at all.
But its easy to treat with 4 subs. Just do what Duke mentions above. He's a modest individual and didn't mention that he makes some of the best subs out there- the Swarm, which comes in sets of 4. Two of them are placed asymmetrically in the room and it is this placement that breaks up standing waves, allowing you to hear all the bass notes at the listening chair.