I did that, starting in 2004 or 2005. I picked up a pair of Yamaha HS80 8” near-field monitors and the companion HS10W 10” studio sub for my computer setup. I had a pair of KEF Q60 bookshelf speakers in my main system. The computer system was driven by an M-Audio Firewire Audio interface with balanced XLR outs.
After moving into a larger place, I removed some components from the HS80 built in amplifiers; basically ripped out the bass limiting circuit to make them perform correctly in a midfield environment. I had already been using them zeroed out with a pro analog EQ and spectrum analyzer.
Later, I bought more, adding a theater processor and eventually totalling out at 7 monitors and 5 of the studio subs. I’ve voiced them not to be flat but to follow the Toole/Olive psychoacoustic response curve, as measured at the listening position, published from research by JBL Labs.
All in all my experience is tremendously positive. Studio monitors are cheap, they take insane amounts of EQ without batting an eyelash, have fantastic off axis response, are amazingly detailed. I’ve stuck with this system for 20 years and find it is more convincing to listen to than friends’ systems costing an order of magnitude more.
If I were to upgrade today, I’d just get better monitors from Genelec or Neumann.