Do 45 RPM records need higher anti-skate setting?

I was playing one of my 45's today and heard Distinct mistracking on one channel only. I increased the skating setting and it was much better. This was only near he beginning of the LP. The LP was a Cannoball Adderly record. Do 45's require higher anti skate setting or is just a peculiarity of this record. The vinyl system is an LP12, Arkiv B and Ekos II, which invariably tracks very well.