My suggestion is to find a quality audio dealer and work with them to build a system that suits your needs and budget. Trying to do this using internet opinion forums and back issues of Stereophile is a fool's errand.The whole system needs to be considered, including the room, programming, and possible upgrade paths. As you develop in this hobby, tastes will change as well as listening habits, and system parameters will change along the way.The wires used to connect the components need only be adequate for the task at hand. More costly wire may alter the presentation, but the effects will be less obvious than spending the same amount of money on an improved front end or speakers. Once you have established a system that suits your needs, experimenting with cables might bring incremental improvements or subtle changes to the sound signature. It might be interesting, but could be expensive (that is for you to decide).Note: A good, high end system can be assembled for less than $10k. So much depends on your circumstances and expectations. Spending more will get you more expensive equipment, but not necessarily better sound, or more importantly, more satisfaction. Synergy is the key concept here. It all must work together.