Personally speaking, I prefer to use some type of an audio point or spike (three per speaker).
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Ditto. Even with the GMA Europas, which I had been assured were so vibrationally inert due to their cast marble enclosures that you wouldn't need spikes, I heard distinct improvements after spiking them on top of Osiris stands. You can do it with the spikes pointing up or down in my experience, though I usually turn them down to avoid scratching the speakers themselves. Every monitor speaker I've heard in my system sounded better spiked on top of the stands.