Mksr - well since you asked...
1- First I would advise you get a copy of Jim Smith's Book "Get Better Sound" and read it from cover to cover.
2- Test your room with analysis software. You will need a laptop, software program and a calibration microphone. You can pay someone else to do this, but cheaper and it's easy to do yourself, and you will learn a lot in the process. There are many sw applications for PC and mac, some free and some $. The free apps are good but not great, so just pick one that has instructions that you can understand and go.
If you are going all digital (as in from a PC or music server), you might simply try using an active room EQ software in the signal path. I am very impressed with a product called Dirac Live Room Correction Suite.
They recently introduced a less expensive, 2-channel only version that IMO works great.
3- After you have tested your room and have an analysis, you can either send it to a professional for guidance ($$$), send it to a room treatment product vendor or learn how to analyze the data yourself. It's not that hard.
4- Treat the room, but don't over-treat. I suggest starting small and adding more if needed. Most rooms your size will benefit from bass traps in the corners. You might also add some absorption and diffusion, but again I recommend starting with a minimal approach and adding more as needed. Don't go overboard with product. You are not going to make a 10x12 room acoustically perfect for all speakers, merely listenable for a select few.
5- Select your speakers, based on your room analysis, room treatments and physical limitations (can you place the speakers against the back wall or can they come out into the room, do they need to be placed on a shelf or ???) If possible, try any speaker first in your room and with your gear before buying, or make sure that you have a good try and buy or return policy.
There are lots and lots of great speakers out there, and many that will work well in your (hopefully now treated) room. But here are some general guidelines that have worked for me in my small room (but YMMV):
- select the smallest speakers that will provide you with the sound that you seek. Standmount monitors work VERY well in small rooms (should be obvious, no?)
- I have found that speakers utilizing a single point source tend to sound better, are easier to place and require less room treatment than widely placed, multiple drivers
- I would try suggest that you avoid dipole or radial speakers, with the possible exception of the Quad 57. The placement requirements are too challenging for a 10x12 room
- think low power amps - SETs or small PP tube amps and low powered MOSFET/OPAMP SS units will work very well if mated to a pair of relatively high efficiency speakers
- if it's to your liking, corner placement and/or or small horns can sound marvelous in a small room
- some may advocate nearfield listening. You can try that - it's not my cup of tea. But if it works for you you might be able to avoid doing anything at all to the room.
I hope that this is useful. Have fun!