I don't have the 5200, but I have the 5000. It may actually be the most valuable component in the system, because it makes the system usable for the rest of the family. Without it, I have to use a selection of 11 remotes with a total of about 650 buttons, used in the right order. I put the system together and I sometimes forget which thing to do when. The reality has become that these systems are now so complex that you need a (little) computer to operate them...
With the RC5000, I've got a button that says "Watch a DVD". It causes the screen to drop, the projector to come on, sets the projector input to component, turns on the prepro and DVD player, sets the prepro to -7dB, and opens the DVD drawer. My wife gets to put the DVD in the drawer, push it in, sit down and press Play. The lights go down, and the movie starts.
Want to play that Diana Krall CD? Press the CDs button, then the name of the album. The lights go back up, the projector goes off, the screen retracts, the CD jukebox powers up and loads the CD, the prepro changes to coax input, and the CD plays at -12dB.
It also knows DirecTV channel codes and all sorts of things.
It is something of a tedious thing to program if you do it yourself, but it's definitely possible.
The 5200 is better than the 5000 because it has more memory (useful for the bigger jukeboxes and more elaborate icons) and more visibly, more hard buttons. It's also got RF.
The RC9200 is even nicer, but the $1200 price tag is kind of out of this world.