Just to give a little more background on my negative experience with the Unison Unico:
Unison Unico CDP
Michell Tecnodec TT, Trichord Dino phono
(also Linn Wakonda/LK140, Jolida 302b, Audio Aero Prima)
It is certainly not like I tried only a few components over the 2-3 months that I owned the Unico. In fact, I wanted to like the amp (nice finish and a remote), but could not get it to sound good using any of the above combinations. I tried a couple of different tubes (the Jan it came with, Mullard, and RCA Cleartop and some others I can't remember). Neither of these helped to improve things much. Also, the previous owner of the Unico had the same Spendors and similar experiences. It is possible that with the right speakers the Unison Unico amp and CDP might be better.
Also, I did here the Unico combo in their showroom at HE in NYC. I don't remember which speakers they did use, but I was not overwhelmed with the sound at HE either. Finally I did see other comments that described the Unico as veiled and lifeless, so it does not seem to be a singular experience.
In any case, I would always try to listen to a component in ones own system. As Arni mentioned, system syergy does play some role.