Statistical significance is not determind if the person testing is able to tell the difference more than 50%. It has been a while since I took statistics but there are a number of variables involved including how many trials were involve. Sometimes it has to occur 90% or more of the time, depending upon the trials. I'm sure those that use statistical analysis can refresh our memory, or I could dust off my 20 year old stats book. Anyhow, I don't fully buy a/b or blind testing. What I do buy is my ear. I don't care what my neighbor hears. I don't have them eat a meal or taste a wine to validate or develop my opinion. I trust my senses. Therefore, If I hear a diffence, then there is a difference. Also, quick testing doesn't always reveil what is happening. That can take time. And, yes I know you can do statistical analysis over time. As to the advantages to a stand, or an isolation device, one item that has been over-looked is resonation. If the item you are using decreases the vibration of the product, both air born and direct, it can have an affect on the sound. Note, I said can. Ultimately, I believe each indivdual should make their own conclusion about the worth of any item. That being whether or not it makes a difference or if it is worth the difference. I use an amp stand. Does it make a difference? Some, but not as much as a change in componet, source, speaker or room treatment. By the way, I made my own for $12.00.