Advice for Neophyte Assembling a System

Greetings. I am in the process of researching system options for a listening room and would greatly appreciate any advice for selecting components. The listening room measures 16'6" long x 17'4" wide (components/speakers against this wall) with a 10' ceiling. Two sides are glass and two are solid. I listen mainly to rock, pop and alternative music and appreciate a good, deep bass. The budget is ~$40k. 

Wondering whether separates or an integrated amp would be the way to go? I've listened to the Wilson Sabrinas driven by a Linn amp (not sure which), which sound great but am wondering what other speaker/amp combinations would be worth auditioning? Would the Esoteric F-03A integrated at 30Wpc be adequate to drive the Sabrinas at moderate to loud levels in a listening room of the above dimensions?

Any thoughts and insight would be sincerely appreciated.

Thanks for your consideration.