Dust has remarkably little effect on solid state electronics, because the voltages are low and the circuits are high current low impedance. Tube electronics are a different matter, because of the high impedance high voltage circuitry. When the voltage gets really high, like for the CRT of a TV set, dust is attracted to the high voltage area, and can actually short it out so that the set won't operate.
Clean it out if that suits you, but don't try to do such a good job that you damage something.
Clean it out if that suits you, but don't try to do such a good job that you damage something.