The Dynaudio Focus 110s replaced $3,000.00 Harbeths which replaced $4,500.00 ProAcs. My room is quite small (11 x 13.5) and I now use a REL sub with very close attention to tuning. The Focuses (Foci?) were just to have something until I made deal on Cremonas or something other montitor in that price range. The 110s are performing so well that my search has slowed considerably. And I've never been a fan of Dynaudio speakers before - always a little clinical for my tastes. By the way, I use a Joule Electra LA150 pre and an EAR 890 tube amp.
Interconnects are all Cardas Golden Refs with TG Audio speakers cables. I am cursed with the ability to hear differences btw wires and cables - these are all more musical (to my ears) than Audience AU24s and Kimber Selects.
I actually really, really like the little 110s. They are more musical and engaging in my system and room than the ProAcs, Harbeths, Merlin TSM-MXs, Spendor 1/3s, Spendor 3/5s. I have not had SF Cremona Auditors for audition as I intended a few months ago but will probably do so. But last night Art Blakey, Gil Evans, and Pancho Sanchez sounded so damn good I'm serioulsy thinking about spending that money on more music.