If the cable length that is required is particularly short, though, e.g. just a couple of feet or so, and/or if the speaker impedance is particularly high, e.g. 10 ohms or more, it might work reasonably well. Also, sometimes performance that is inaccurate to some degree can turn out to be subjectively preferable, or can compensate for inaccuracies elsewhere in the system or in the recording.
In any event, I would not envision any possibility of damage if you were to try it, assuming of course that no shorts are inadvertently introduced. Although if high power levels are being sent to the speakers more or less continuously the power dissipated in the resistance of the cables might cause them to get somewhat warm.