I guess I don't totally understand the question. Whole houses are wired using 12 ga. Romex and many of those circuits serve much more than 150 watt devices (combined).
That said, I like big wires, and when I put in a dedicated AC system, I used 6 ga. stranded copper for 60 ft. from my main breaker panel to a sub-main dedicated breaker box. I knew the 6 ga. was "overkill", but it was more or less in place so I used it-- worked great and sounds good.
I don't know what gauge my Syn. Res. Sig. #2 speaker cables are but they are about 1/2" or more thick. Bigger can't hurt, and if you go large, you won't want to replace it later. Good Luck. Craig
That said, I like big wires, and when I put in a dedicated AC system, I used 6 ga. stranded copper for 60 ft. from my main breaker panel to a sub-main dedicated breaker box. I knew the 6 ga. was "overkill", but it was more or less in place so I used it-- worked great and sounds good.
I don't know what gauge my Syn. Res. Sig. #2 speaker cables are but they are about 1/2" or more thick. Bigger can't hurt, and if you go large, you won't want to replace it later. Good Luck. Craig