$5k or less speakers (used or new)?

Room is: 16’ x 22’ 9’ tall

I am running two emotiva UPA-1 mono block amps pushing Phase Technology PC 3.5 speakers. 

They are larger bookshelf speakers that absolutely fill that large room without a doubt. 
I like a more smooth natural sounding speaker. 
I’ve auditioned the Paradigm Persona line and the tweeter seems to irritate me after a bit. 
I’m happy with my current speakers but I think I want something larger to play louder. 😜

Salk Song 3 BeAT or if you can stretch for more bass, Song 3 Encore.

LSA Statement 20s available here new for $3999 on sale and come with nice speaker cables as a bonus, and they offer a 30-day, in-home trial. Part Time Audiophile did a nice review of them where they compared favorably with the reviewer’s $25k reference speakers, and their sound characteristics seem inline with what you’re looking for. I think Salk is also an excellent recommendation. Best of luck.

Another Salk recommendation. Also the great Magnepan 1.7’s. 

Over time, I got a feeling that it is hard to pick bad speaker for $5000. It comes down to your preference and desired sound.