Well if the tube has been in that amp for seven years then, yes, it's possible for the tube to fail. Even small signal tubes wear out and need to be replaced, usually after 8-10,000 hours. The question is, was anything else damaged when the tube failed? Try installing a new 12AX7. I recommend the JJ803S. Hopefully it works and away you go. You can also email the good people at Vox and ask them.
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